In recent years, rapid improvement of cloud computing convinced everyone accept it as a powerful substitution. Nowadays, more and more organizations are getting used to create private clouds, on the other hand, public clouds must be robust enough to handle scientific computing and computing sensitive requests of users in an efficient and cost effective manner. Apart from all these necessities, it is intellectual to improve the cloud infrastructure performance by appropriate choices. In this paper we are going to evaluate the performance of various hypervisors, including VMware ESXi, KVM, Xen, Oracle VirtualBox, and VMware Workstation using HPC Challenge (HPCC) benchmark SUITE and Open MPI in order to represent solutions for virtualization layer of cloud computing architecture and clusters.